The second involves the sense of smell, which largely dictates the flavor of most foods. It is conceivable that your starting to take captopril is a red herring and you might be noticing a change even if you weren't taking the drug. Beginning around age 60, many people experience a gradual loss of taste and smell. Two other possibilities: The first has to do with age. Noncardiac drugs with this side effect include antibiotics, steroids, antidepressants and other mood- or behavior-stabilizing medications, and thyroid drugs.Ĭardiovascular medications reported to affect taste:Ĭaptopril (Capoten), enalapril (Vasotec), lisinopril (Prinivil, Zestril)Īmiodarone (Cordarone), flecainide (Tambocor), procainamide (Procanbid), propafenone (Rythmol), sotalol (Betapace)ĭiltiazem (Cardizem, others), nifedipine (Procardia, others)Ītorvastatin (Lipitor), fluvastatin (Lescol), lovastatin (Mevacor), pravastatin (Pravachol), simvastatin (Zocor)Īmiloride (Moduretic), spironolactone (Aldactone) Other cardiovascular drugs that have been reported to alter taste include statins, clopidogrel (Plavix), and various beta blockers, calcium-channel blockers, and rhythm-controlling drugs (see list). Fortunately, changes in taste are not as common with the most frequently used diuretics, hydrochlorothiazide and chlorthalidone. The potassium-sparing diuretic amiloride can cause a persistent bitter taste. Because diuretics prompt the kidneys to remove water from the body, they can make the mouth dry. Some people notice a diminished sense of taste.Īlthough captopril is a likely suspect, it is possible that your diuretic may be causing or contributing to the problem. In others, it makes sweet foods taste salty. In some people, captopril causes a long-lasting sensation of bitterness or saltiness.
The ACE inhibitor captopril (Capoten) is in this group. They usually do this by directly affecting taste receptors, by changing the way the taste buds send and receive nerve impulses, or by changing the amount or chemical composition of saliva. Am I imagining this, or could the new drug be affecting my sense of taste? If it is, what can I do about it?Ī. Hundreds of prescription and over-the-counter medicines can alter the sense of taste. The only big change in my health is that I started taking Capoten on top of the diuretic I have been taking for some time to control my blood pressure. Q. My sense of taste isn't as good as it was a few months ago.
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